S100A8/A9 Complex (Calprotectin) 抗体 (AA 1-100)
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Quick Overview for S100A8/A9 Complex (Calprotectin) 抗体 (AA 1-100) (ABIN7864425)
抗原
See all S100A8/A9 Complex (Calprotectin) (S100A8/A9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-100
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原理
- Calprotectin / MRP14 / S100A9 / Calgranulin B Antibody
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特异性
- This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer s cells of the liver and Langerhan s cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. It plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa1-100) of human S100A9 protein (exact sequence is proprietary)
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亚型
- IgG2, kappa
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anti-Calprotectin (S100A8/A9) antibody
S100A8/A9 适用: 人, Pig, 大鼠, 小鼠, Cow, Cat, 犬, 豚鼠, 猴, 兔, 马, Baboon, 山羊 IHC 宿主: 兔 Monoclonal MAC3157R unconjugated Recombinant Antibody
anti-Calprotectin (S100A8/A9) antibodyS100A8/A9 适用: 人, Pig, 大鼠, 小鼠, Cow, Cat, 犬, 豚鼠, 猴, 兔, 马, Baboon, 山羊 IHC 宿主: 小鼠 Monoclonal rMAC3781 unconjugated Recombinant Antibody
anti-Calprotectin (S100A8/A9) (AA 1-114) antibodyS100A8/A9 适用: 人 IHC, WB, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Calprotectin (S100A8/A9) antibodyS100A8/A9 适用: 人, Pig, 大鼠, 小鼠, Cow, Cat, 犬, 豚鼠, 猴, 兔, 马, Baboon, 山羊 IHC, FACS, IF 宿主: 小鼠 Monoclonal SPM281 unconjugated
anti-Calprotectin (S100A8/A9) antibodyAnimal-Free S100A8/A9 适用: 人 ELISA 宿主: 小鼠 Monoclonal AB467-1-A05 unconjugated Recombinant Antibody
anti-Calprotectin (S100A8/A9) antibodyS100A8/A9 适用: 人 IHC, WB, ELISA 宿主: 小鼠 Monoclonal 69-6-1 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))
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别名
- Calprotectin
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背景
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S100-A9, MRP14, calgranulin-B, calprotectin L1H subunit, leukocyte L1 complex heavy chain, migration inhibitory factor-related protein 14, S100 calcium-binding protein A9 (calgranulin B)
Liver or histiocytoma.
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分子量
- 14kDa
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基因ID
- 6280, 112405
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UniProt
- P06702
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途径
- S100 Proteins
抗原
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