Recombinant Cadherin-16 抗体 (AA 350-550)
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Quick Overview for Recombinant Cadherin-16 抗体 (AA 350-550) (ABIN7857995)
抗原
See all Cadherin-16 (CDH16) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 350-550
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原理
- Recombinant Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Antibody
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特异性
- This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. 79oΩKsp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
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纯化方法
- 200ug/ml of Ab purified by Protein A.
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免疫原
- Recombinant fragment (around aa350-550) of human CDH16 protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Cadherin-16 (CDH16)
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别名
- Ksp-Cadherin
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背景
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Cadherin-16 (CDH16), Kidney-specific cadherin, Ksp-cadherin antibody
Human kidney or renal cell carcinoma.
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分子量
- 130kDa
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基因ID
- 1014, 513660
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UniProt
- O75309
抗原
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