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Recombinant EpCAM 抗体 (Cytoplasmic Domain)

The 兔 单克隆 anti-EpCAM antibody (Clone EGP40-7035R) (ABIN7863105) specifically detects EpCAM in IHC. The antibody is reactive with 人, Cat 和 犬 samples.
产品编号 ABIN7863105
发货至: 中国
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Quick Overview for Recombinant EpCAM 抗体 (Cytoplasmic Domain) (ABIN7863105)

抗原

See all EpCAM (EPCAM) 抗体
EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

抗体类型

Recombinant Antibody

适用

  • 472
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人, Cat, 犬

宿主

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  • 19
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  • 1
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克隆类型

  • 396
  • 121
  • 3
单克隆

标记

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This EpCAM antibody is un-conjugated

应用范围

  • 306
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Immunohistochemistry (IHC)

克隆位点

EGP40-7035R
  • 抗原表位

    • 86
    • 53
    • 50
    • 35
    • 27
    • 19
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    AA 289-314, Cytoplasmic Domain

    原理

    Recombinant EpCAM / CD326 (Cytoplasmic Domain) (Epithelial Marker) Antibody

    特异性

    Epitope of this MAb is mapped between aa 202-212 of EGP40, which is a 40-43 kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. Antibody to Ep-CAM has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

    纯化方法

    200ug/ml of Ab purified by Protein A.

    免疫原

    Recombinant fragment from cytoplasmic domain (around aa 289-314) of human EpCAM (exact sequence is proprietary)

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

    别名

    EpCAM

    背景

    Adenocarcinoma-associated Antigen, Cell Surface Glycoprotein Trop-1, EGP2, EGP314, ESA, Epithelial Glycoprotein 314, KSA, TROP1, Epithelial Cell Adhesion Molecule, Tumor-associated Calcium Signal Transducer 1 (TACSTD1)

    HT29 cells. Human colon or breast., MCF-7

    分子量

    40-43kDa

    基因ID

    4072, 542050

    UniProt

    P16422
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