Recombinant Inhibin alpha 抗体 (AA 233-362)
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Quick Overview for Recombinant Inhibin alpha 抗体 (AA 233-362) (ABIN7863030)
抗原
See all Inhibin alpha (INHA) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 233-362
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Expression System
- HEK-293 Cells
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原理
- Recombinant Inhibin, alpha (INHA) (Gonadal Cell Marker) Antibody
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特异性
- It recognizes a 47 kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same °™ subunit, covalently linked to 1 of 2 distinct subunits, æ-°™ or æ- æ. Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein, inhibin belongs to the transforming growth factor æ (TFG æ) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.
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纯化方法
- 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.
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免疫原
- Recombinant fragment of human Inhibin alpha protein (around aa 233-362) (exact sequence is proprietary)
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Inhibin alpha (INHA) (Inhibin, alpha (INHA))
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别名
- Inhibin, alpha
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背景
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A inhibin subunit, IHA, inhA, Inhibin alpha chain, Inhibin alpha subunit
Human prostate or testis.
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分子量
- 47kDa
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基因ID
- 3623, 407506
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UniProt
- P05111
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途径
- Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
抗原
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