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Recombinant Selectin E/CD62e 抗体

The 小鼠 单克隆 anti-Selectin E/CD62e antibody is suitable to detect Selectin E/CD62e in samples from 人. It has been validated for IHC.
产品编号 ABIN7857825
发货至: 中国
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Quick Overview for Recombinant Selectin E/CD62e 抗体 (ABIN7857825)

抗原

See all Selectin E/CD62e (SELE) 抗体
Selectin E/CD62e (SELE) (Selectin E (SELE))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Selectin E/CD62e antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

R16G4
  • Expression System

    CHO Cells

    原理

    Recombinant CD62E / Selectin E (SELE) / ELAM-1 Antibody

    特异性

    CD62E is also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) or E-selectin. It is a type I membrane protein that belongs to the selectin family of surface molecules (along with CD62L and CD62P). CD62E is expressed on cytokine induced endothelial cells and mediates their binding to leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial tethering and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues. The main ligands recognized by CD62E are oligosaccharides related to sialyl-lewis X.

    纯化方法

    200ug/ml of Ab produced in CHO cell mammalian-based expression system.

    免疫原

    Prokaryotic recombinant fusion protein corresponding to the cysteine-rich complement control protein domains of the CD62E molecule

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    Selectin E/CD62e (SELE) (Selectin E (SELE))

    别名

    CD62E

    背景

    CD62E, ELAM1, SELE, E-selectin, ELAM-1, LECAM2

    Human bone marrow, lymph node, inflamed tonsil, heart or liver.

    分子量

    115kDa

    基因ID

    6401

    UniProt

    P16581

    途径

    Thromboxane A2 Receptor Signaling
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