Recombinant Selectin E/CD62e 抗体
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Quick Overview for Recombinant Selectin E/CD62e 抗体 (ABIN7857825)
抗原
See all Selectin E/CD62e (SELE) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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Expression System
- CHO Cells
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原理
- Recombinant CD62E / Selectin E (SELE) / ELAM-1 Antibody
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特异性
- CD62E is also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) or E-selectin. It is a type I membrane protein that belongs to the selectin family of surface molecules (along with CD62L and CD62P). CD62E is expressed on cytokine induced endothelial cells and mediates their binding to leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial tethering and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues. The main ligands recognized by CD62E are oligosaccharides related to sialyl-lewis X.
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纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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免疫原
- Prokaryotic recombinant fusion protein corresponding to the cysteine-rich complement control protein domains of the CD62E molecule
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Selectin E/CD62e (SELE) (Selectin E (SELE))
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别名
- CD62E
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背景
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CD62E, ELAM1, SELE, E-selectin, ELAM-1, LECAM2
Human bone marrow, lymph node, inflamed tonsil, heart or liver.
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分子量
- 115kDa
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基因ID
- 6401
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UniProt
- P16581
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途径
- Thromboxane A2 Receptor Signaling
抗原
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