Recombinant HSP90 抗体
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北京 101111
Quick Overview for Recombinant HSP90 抗体 (ABIN7857794)
抗原
See all HSP90 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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Expression System
- CHO Cells
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原理
- Recombinant Heat Shock 27kDa Protein 1 Antibody
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特异性
- HSP27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50 % homology with low molecular weight Drosophila HSPs and mammalian ±-crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore, HSP27 may be useful in classifying various hormone sensitive tumors.
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纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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免疫原
- Prokaryotic recombinant protein corresponding to the full length human heat shock protein 27 molecule
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- HSP90 (Heat Shock Protein 90 (HSP90))
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别名
- Heat Shock Protein 1
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背景
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Heat shock 27 kDa protein, Estrogen-regulated 24 kDa protein, Heat shock 25 kDa protein 1, Heat shock 28 kDa protein 1, Heat shock protein beta-1, HMN2B, Hsp25, Hsp28, HspB1, Stress-responsive protein 27 (SRP27)
~50 % of breast carcinomas are positive for hsp27 especially those that are ER and/or PgR positive.
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分子量
- 27kDa
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基因ID
- 3315, 520973
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UniProt
- P04792
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途径
- M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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