Recombinant CRYAB 抗体
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Quick Overview for Recombinant CRYAB 抗体 (ABIN7865474)
抗原
See all CRYAB 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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Expression System
- CHO Cells
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原理
- Recombinant Crystallin Alpha B / CRYAB (Marker of Metaplastic Carcinoma) Antibody
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特异性
- Alpha B crystallin is a lens protein which has some homology with the small heat shock proteins. It is expressed in tissues such as skeletal muscle, cardiac muscle, smooth muscle, renal tubular epithelium, Schwann cells, glial cells, thyroid epithelium, colonic epithelium and stratified squamous epithelium. Alpha B crystallin is also reported to be found in ubiquitinated intermediate filament inclusion bodies, such as Lewy bodies (neurofilaments), Rosenthal fibres (glial filaments) and Mallory bodies (cytokeratins). Alpha B crystallin is rarely found in neurofibrillary tangles. The role of Alpha B crystallin in these inclusion bodies is unknown, however, it may function as an accessory protein for intermediate filament aggregation.
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纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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免疫原
- Synthetic peptide hemocyanin conjugate. The peptide corresponds to human alpha B crystallin amino acids 1 to 10.
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- CRYAB (Crystallin, alpha B (CRYAB))
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别名
- Crystallin Alpha B
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背景
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AACRYA, Alpha B crystallin, Alpha-crystallin B chain, CRYA2, CTTP2, Heat shock 20 kD like protein, Heat shock protein beta-5, HspB5, Renal carcinoma antigen NY REN 27, Rosenthal fiber component
Human heart, kidney or brain.
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分子量
- Predicted: 20kDa, Observed: 22-30kDa
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基因ID
- 1410, 53454
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UniProt
- P02511
抗原
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