Recombinant CD44v6 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant CD44v6 抗体 (ABIN7857764)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
Expression System
- CHO Cells
-
原理
- Recombinant CD44v6 (Marker of Tumor Metastasis) Antibody
-
特异性
- This antibody recognizes an epitope encoded by exon v6 on the variant portion of human CD44. The CD44 Molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA.The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.
-
纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
-
免疫原
- Recombinant fragment corresponding to the v3-v10 domain of human CD44
-
亚型
- IgG, kappa
-
-
anti-CD44v6 antibody (FITC)
适用: 人 FACS 宿主: 小鼠 Monoclonal VFF-7 FITC
anti-CD44v6 antibody适用: 人 FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal CD44v6-1246 unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
-
- CD44v6
-
背景
-
LHR, BA-1, chondroitin sulfate proteoglycan 8 (CSPG8), Epican, Extracellular Matrix Receptor III (ECM III), GP90 Lymphocyte Homing Adhesion Receptor, HCAM, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan Sulfate Proteoglycan, Hermes Antigen, HAS, HUTCH I, Hyaluronate Receptor, Indian blood group, Inlu Related p80 Glycoprotein, Ly 24, MDU2, MDU3, MIC4, MUTCH I, Phagocytic Glycoprotein 1 (PGP-1)
Human cervix or tongue squamous cell carcinoma.
-
分子量
- 80-95kDa
-
基因ID
- 960, 502328
-
UniProt
- P16070
抗原
-
