Recombinant Cathepsin D 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant Cathepsin D 抗体 (ABIN7865162)
抗原
See all Cathepsin D (CTSD) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
Expression System
- CHO Cells
-
原理
- Recombinant Cathepsin D (Tumor Marker) Antibody
-
特异性
- Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 52 kDa preprocathepsin D that is cleaved and glycosylated to form a 48 kDa procathepsin D and then further cleaved to produce 34 kDa and 14 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
-
纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
-
免疫原
- His-tagged CTSD protein
-
亚型
- IgG, kappa
-
-
anti-Cathepsin D (CTSD) (C-Term) antibody
CTSD 适用: 人, 小鼠, 大鼠, 猴, Hamster, Cow, Pig, 兔, 犬, 马, 豚鼠, Avian, Cat, 小鸡, 驴, 山羊, 绵羊 WB, IF, IHC (p), IHC (fro), IEM 宿主: 山羊 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 66-410) antibodyCTSD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 26-412) antibodyCTSD 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 3F12-1B9 unconjugated
anti-Cathepsin D (CTSD) (AA 1-412) antibodyCTSD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 104-250) antibodyCTSD 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal CTSD-3082 unconjugated
anti-Cathepsin D (CTSD) (AA 120-407) antibodyCTSD 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 21-412) antibodyCTSD 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C7 unconjugated
anti-Cathepsin D (CTSD) (AA 104-250) antibodyCTSD 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal CTSD-3276 unconjugated
anti-Cathepsin D (CTSD) (AA 201-412) antibodyCTSD 适用: 人 WB, IHC, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (C-Term) antibodyCTSD 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 豚鼠, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
有效期
- 24 months
-
-
- Cathepsin D (CTSD)
-
别名
- Cathepsin D
-
背景
-
CatD, Cathepsin D, Ceroid lipofuscinosis neuronal 10, CLN10, CPSD, Epididymis secretory sperm binding protein Li 130P, Lysosomal aspartyl peptidase, Lysosomal aspartyl protease
Human kidney, liver, lung or breast tissues. Brain, Heart, Skeletal muscle, Skin or Pancreas
-
分子量
- 48kDa (Procathepsin D), 34kDa (Cathepsin D), 14kDa (Cathepsin D)
-
基因ID
- 1509, 654447
-
UniProt
- P07339
-
途径
- Peptide Hormone Metabolism
抗原
-
