Recombinant SV2A 抗体 (Cytoplasmic Domain, N-Term)
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Quick Overview for Recombinant SV2A 抗体 (Cytoplasmic Domain, N-Term) (ABIN7857725)
抗原
See all SV2A 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Cytoplasmic Domain, N-Term
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Expression System
- CHO Cells
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原理
- Recombinant Synaptic Vesicle Protein 2 (SV2) (Marker of Neuroendocrine Cells) Antibody
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特异性
- Synaptic vesicle protein 2 (SV2) is an integral membrane glycoprotein. It is required for normal neurotransmission and may play a role in the regulation of calcium-stimulated exocytosis. SV2 exists in three forms, SV2A, SV2B and SV2C, each containing 12 transmembrane spanning regions. SV2 proteins are among the most abundant and conserved components of synaptic vesicles in vertebrates. They are present on all small synaptic vesicles independent of transmitter type. SV2A and SV2B are widely distributed in the nervous system, whereas SV2C is only observed in a small number of neurons in a few areas of the brain. SV2A is expressed at the highest levels in subcortical regions, whereas the highest level of expression of SV2B is in the cortex and hippocampus. SV2 is expressed on secretory vesicles of neuroendocrine cells in the GI tract, pancreas, anterior pituitary gland, thyroid, parathyroid and adrenal medulla and also in exocrine chief cells of gastric mucosa.
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纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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免疫原
- Prokaryotic recombinant protein corresponding to the N-terminal cytoplasmic domain of the human synaptic vesicle 2A molecule which shares some regions of homology with the SV2B molecule
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))
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别名
- Synaptic Vesicle Protein 2
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背景
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KIAA0736 | PSEC0174 | SV2A | Synaptic vesicle glycoprotein 2A
Human brain.
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分子量
- 93kDa
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基因ID
- 9900
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UniProt
- Q7L0J3
抗原
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