Recombinant Renal Cell Carcinoma (Gp200) (AA 80-100), (N-Term) 抗体
This 兔 单克隆 antibody specifically detects Renal Cell Carcinoma (Gp200) in IHC 和 WB. It exhibits reactivity toward 人, 大鼠 和 豚鼠.
产品编号 ABIN7865169
发货至:
中国
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Quick Overview for Recombinant Renal Cell Carcinoma (Gp200) (AA 80-100), (N-Term) 抗体 (ABIN7865169)
抗原
Renal Cell Carcinoma (Gp200)
抗体类型
Recombinant Antibody
适用
人, 大鼠, 豚鼠
宿主
兔
克隆类型
单克隆
标记
非结合性
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
克隆位点
CA9-9621R
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抗原表位
- AA 80-100, N-Term
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Expression System
- CHO Cells
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原理
- Recombinant Renal Cell Carcinoma (Carbonic Anhydrase IX) Antibody
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特异性
- Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93 % of primary and 84 % of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
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纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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免疫原
- Extracellular N-terminal proteoglycan-like region. Epitope is between aa80-100.
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亚型
- IgG, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Renal Cell Carcinoma (Gp200)
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别名
- Renal Cell Carcinoma
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背景
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CA-IX, CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, Carbonic anhydrase IX, Carbonic dehydratase, G250, Membrane antigen MN, P54/58N, pMW1, RCC-associated antigen G250, Renal cell carcinoma-associated antigen G250
HeLa cells. Normal kidney or Human Stomach, Rat Stomach or Guinea pig Stomach (WB) renal cell carcinoma (IHC).
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分子量
- 55kDa
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基因ID
- 768, 63287
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UniProt
- Q16790
抗原
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