Recombinant HSPH1 抗体 (C-Term)
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Quick Overview for Recombinant HSPH1 抗体 (C-Term) (ABIN7857690)
抗原
See all HSPH1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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Expression System
- CHO Cells
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原理
- Recombinant Heat Shock Protein 105 kDa / HSP105 (Basaloid Skin Tumor Marker) Antibody
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特异性
- Heat shock protein (HSP) 105 exists as two isoforms, alpha and beta which belong to the HSP105/HSP110 protein family. HSP105 acts as both a chaperone to prevent thermal aggregation of proteins and as a regulator of mammalian cells. The HSP105 isoforms are found in the cytoplasm but not in the nucleoli under non-stressed and stressed conditions. In rodents, HSP105 isoforms are moderately expressed in the adrenal glands, spleen, liver and heart and both are markedly increased after heat shock. In the testis, HSP105 is specifically localized in the cytoplasm of germ cells and may translocate to the nucleus after heat shock. The most abundant expression occurs in the brain with nuclear and cytoplasmic expression in nearly all neurones, oligodendrocytes, microglia and astrocytes. Increased expression during embryogenesis suggests that HSP105 may have an important role during mouse embryo development.
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纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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免疫原
- Prokaryotic recombinant protein of 31 kD corresponding to the C-terminus of the heat shock protein 105 molecule
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))
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别名
- Heat Shock Protein 105 kDa
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背景
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HSP105, HSP110, KIAA0201, HSPH1, Heat shock protein 105 kDa, Antigen NY-CO-25, Heat shock 110 kDa protein, Heat shock protein family H member 1
Human brain or testis.
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分子量
- 105kDa
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基因ID
- 10808
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UniProt
- Q92598
抗原
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