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Recombinant PAX7 抗体 (AA 301-505)

The 小鼠 单克隆 anti-PAX7 antibody (Clone rPAX7-9325) (ABIN7865124) specifically detects PAX7 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7865124
发货至: 中国
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Quick Overview for Recombinant PAX7 抗体 (AA 301-505) (ABIN7865124)

抗原

See all PAX7 抗体
PAX7 (Paired Box 7 (PAX7))

抗体类型

Recombinant Antibody

适用

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宿主

  • 87
  • 46
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小鼠

克隆类型

  • 68
  • 67
单克隆

标记

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This PAX7 antibody is un-conjugated

应用范围

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  • 7
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Immunohistochemistry (IHC)

克隆位点

RPAX7-9325
  • 抗原表位

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    AA 301-505

    Expression System

    CHO Cells

    原理

    Recombinant PAX7 (Rhabdomyosarcoma Marker) Antibody

    特异性

    The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

    纯化方法

    200ug/ml of Ab produced in CHO cell mammalian-based expression system.

    免疫原

    Recombinant fragment (aa301-505) of human PAX7 protein (exact sequence is proprietary)

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    PAX7 (Paired Box 7 (PAX7))

    别名

    PAX7

    背景

    HUP1, Paired box gene 7, Paired box homeotic gene 7, Paired domain gene HuP1, PAX7 transcriptional factor, PAX7/FKHR fusion gene, PAX7B, RMS2

    Human rhabdomyosarcoma (RMS) or testicular carcinoma.

    分子量

    57kDa

    基因ID

    5081, 113253

    UniProt

    P23759
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