Recombinant CD147 抗体 (AA 100-300)
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Quick Overview for Recombinant CD147 抗体 (AA 100-300) (ABIN7865095)
抗原
See all CD147 (BSG) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 100-300
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Expression System
- CHO Cells
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原理
- Recombinant CD147 / BSG / EMMPRIN / Neurothelin Antibody
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特异性
- This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
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纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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免疫原
- Recombinant fragment (around aa100-300) of human BSG protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
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别名
- CD147
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背景
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5A11 Antigen, 5F7, Basigin, Blood brain barrier HT7 antigen BSG, Extracellular Matrix Metalloproteinase Inducer (EMMPRIN), Leukocyte Activation Antigen M6, Neurothelin, OK Blood Group Antigen, TCSF, Tumor Cell-derived Collagenase Stimulatory Factor
Human renal cell carcinoma, ovarian carcinoma or melanoma. HeLa cells. MCF7, Human Brain, Human Heart, Human Intestine, Human Kidney
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分子量
- 35kDa (non-reduced), 40kDa (reduced)
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基因ID
- 682, 501293
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UniProt
- P35613
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途径
- S100 Proteins
抗原
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