ASIC1 抗体 (Biotin)
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- 抗原 See all ASIC1 (ACCN2) 抗体
- ASIC1 (ACCN2) (Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ASIC1 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ASIC1
- 亚型
- IgG
- Top Product
- Discover our top product ACCN2 Primary Antibody
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anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (N-Term) antibody
ACCN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (C-Term) antibodyVerified ACCN2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibodyACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 unconjugated
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (HRP)ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 HRP
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (FITC)ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 FITC
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (Alkaline Phosphatase (AP))ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 Alkaline Phosphatase (AP)
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (Biotin)ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 Biotin
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (PE)ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 PE
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (APC)ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 APC
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (PerCP)ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 PerCP
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- 应用备注
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WB: 1:100-1000, IHC-P: 1:100-500
Optimal working dilution should be determined by the investigator. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- ASIC1 (ACCN2) (Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))
- 别名
- Asic1/Bnac2/Asic1a (ACCN2 产品)
- 别名
- ACCN2 antibody, ASIC antibody, BNaC2 antibody, Accn2 antibody, ASIC1 antibody, AI843610 antibody, ASIC1a antibody, B530003N02Rik antibody, acid sensing ion channel subunit 1 antibody, acid-sensing (proton-gated) ion channel 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 antibody, ASIC1 antibody, Asic1 antibody, asic1 antibody, SMARCD1 antibody
- 背景
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Synonyms: Acid-sensing ion channel 1, ASICs1, Acid sensing ion channel 1, Acid sensing ion channel 1a protein, Acid sensing ion channel, AI843610, Amiloride sensitive cation channel 2 neuronal, ASIC, ASIC1, ASIC1A, B530003N02Rik, BNAC2, Brain sodium channel 2, Cation channel amiloride sensitive neuronal 2, hBNaC2.
Background: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Ca(2+), Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Mediates glutamate-independent Ca(2+) entry into neurons upon acidosis. This Ca(2+) overloading is toxic for cortical neurons and may be in part responsible for ischemic brain injury. Heteromeric channel assembly seems to modulate channel properties. Functions as a postsynaptic proton receptor that influences intracellular Ca(2+) concentration and calmodulin-dependent protein kinase II phosphorylation and thereby the density of dendritic spines. Modulates activity in the circuits underlying innate fear.
- 基因ID
- 41
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