Lipocalin 2 抗体
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北京 101111
Quick Overview for Lipocalin 2 抗体 (ABIN7849772)
抗原
See all Lipocalin 2 (LCN2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Monoclonal Anti-NGAL (Capture Ab)
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特异性
- It specifically recognize the human NGAL.
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产品特性
- This antibody may be used as Capture Ab in antibody pair experiments such as ELISA.
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纯化方法
- Protein A or G purified
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纯度
- >95 % by HPLC & SDS-PAGE
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免疫原
- Recombinant human NGAL.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M PBS ( pH 7.4) without preservative.
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储存液
- Without preservative
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注意事项
- Avoid repeated freeze and thaw cycles.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20°C for long term (at least one year). Avoid repeated freeze and thaw cycles.
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有效期
- 12 months
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- Lipocalin 2 (LCN2)
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别名
- NGAL
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背景
- Lipocalin-2 (LCN2), also known as oncogene 24p3 or neutrophil gelatinase-associated lipocalin (NGAL), is a protein associated with neutrophil gelatinase. The 25-kD LCN2 protein is believed to bind small lipophilic substances such as bacteria-derived lipopolysaccharide (LPS) and formylpeptides and may function as a modulator of inflammation. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor.
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途径
- Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis
抗原
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