HIV-1 p24 抗体
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Quick Overview for HIV-1 p24 抗体 (ABIN7849766)
抗原
See all HIV-1 p24 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Monoclonal Anti- HIV-1 p24 (Detection Ab)
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产品特性
- This antibody may be used as in antibody pair experiments such as ELISA.
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纯化方法
- Protein A or G purified
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纯度
- >95 % by HPLC & SDS-PAGE
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免疫原
- Recombinant human HIV-1 p24 Protein (Expression system with E.Coli).
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亚型
- IgG
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anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (AA 48-62) antibody
HIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB, IF 宿主: 小鼠 Monoclonal 5 unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (full length) antibodyHIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB, IP, DB 宿主: 豚鼠 Polyclonal unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (AA 165-231), (C-Term) antibodyHIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB 宿主: 小鼠 Monoclonal N13 unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (AA 1-104), (N-Term) antibodyHIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB 宿主: 小鼠 Monoclonal N29 unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (AA 165-231), (C-Term) antibodyHIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB 宿主: 小鼠 Monoclonal 2N44 unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (AA 74-84) antibodyHIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB 宿主: 小鼠 Monoclonal 2N34 unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) (AA 80-90) antibodyHIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB 宿主: 小鼠 Monoclonal 2N32 unconjugated
anti-Human Immunodeficiency Virus 1 Capsid (HIV-1 p24) antibody (Biotin)HIV-1 p24 适用: Human Immunodeficiency Virus (HIV) ELISA, WB, IF, IP 宿主: 兔 Polyclonal Biotin
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.9 % NaCl without preservative.
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储存液
- Without preservative
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注意事项
- Avoid repeated freeze and thaw cycles.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20°C for long term (at least for one year). Avoid repeated freeze and thaw cycles.
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有效期
- 12 months
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- HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))
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别名
- HIV-1 p24
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物质类
- Viral Protein
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背景
- Acquired immune deficiency syndrome (HIV/AIDS) has been a major global health concern for over 38 years. No safe and effective preventive or therapeutic vaccine has been developed although many products have been investigated. Computational methods have facilitated vaccine developments in recent decades. Among HIV-1 proteins, p24 and Nef are two suitable targets to provoke the cellular immune response. The predicted fusion protein, p24-AAY-Nef in a truncated form with a high rate of T cell epitopes and high conservancy rate among different clades, provides a helpful model for developing a therapeutic vaccine candidate against HIV-1. HIV-1 infection of macrophages leads to the sequestration of newly formed viruses in intracellular plasma membrane-connected structures termed virus-containing compartments (VCCs), where virions remain infectious and hidden from immune surveillance. HIV-1 infection of macrophages leads to the sequestration of newly formed viruses in virus-containing compartments (VCCs), where virions remain infectious and hidden from immune surveillance. The transmembrane domain of Vpu and two motifs of the Vpu cytoplasmic domain are required for these functions. These motifs were notably involved in the control of the volume of VCCs by Vpu but were dispensable for the prevention of the specific accumulation of BST2 in these structures.
抗原
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