D-Dimer 抗体
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北京 101111
Quick Overview for D-Dimer 抗体 (ABIN7849757)
抗原
See all D-Dimer 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Monoclonal Anti-D-dimer (Detection Ab)
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特异性
- It specifically recognize human D-dimer antigen, and does not cross react with BSA, but has week cross-reactivity withfibrinogen.
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产品特性
- This antibody may be used as in antibody pair experiments such as ELISA.
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纯化方法
- Protein A or G purified
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纯度
- >95 % by HPLC & SDS-PAGE
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免疫原
- Human D-dimer protein.
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M PBS ( pH 7.4) without preservative.
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储存液
- Without preservative
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注意事项
- Avoid repeated freeze and thaw cycles.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20°C for long term (at least one year). Avoid repeated freeze and thaw cycles.
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有效期
- 12 months
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- D-Dimer
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背景
- D-dimer is a fibrin degradation product (or FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two crosslinked D fragments of the fibrin protein. The D-dimer antigen is a unique marker of fibrin degradation that is formed by the sequential action of 3 enzymes: thrombin, factor XIIIa, and plasmin. Its concentration may be determined by a blood test to help diagnose thrombosis. Since its introduction in the 1990s, it has become an important test performed in patients suspected of thrombotic disorders. While a negative result practically rules out thrombosis, a positive result can indicate thrombosis but does not rule out other potential causes. Its main use, therefore, is to exclude thromboembolic disease where the probability is low. In addition, it is used in the diagnosis of the blood disorder disseminated intravascular coagulation.
抗原
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