AMH 抗体
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北京 101111
Quick Overview for AMH 抗体 (ABIN7849751)
抗原
See all AMH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Monoclonal Anti- Muellerian-inhibiting factor, AMH (Detection Ab)
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产品特性
- This antibody may be used as in antibody pair experiments such as ELISA.
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纯化方法
- Protein A or G purified
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纯度
- >95 % by HPLC & SDS-PAGE
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免疫原
- Recombinant protein.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.9 % NaCl without preservative.
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储存液
- Without preservative
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注意事项
- Avoid repeated freeze and thaw cycles.
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储存条件
- 4 °C
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储存方法
- Aliquot and store at 2-8°C for long term (at least one year). Avoid repeated freeze and thaw cycles.
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有效期
- 12 months
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- AMH (Anti-Mullerian Hormone (AMH))
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别名
- Muellerian-inhibiting factor
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背景
- Anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting hormone (MIH), is a glycoprotein hormone structurally related to inhibin and activin from the transforming growth factor beta superfamily, whose key roles are in growth differentiation and folliculogenesis. In humans, it is encoded by the AMH gene, on chromosome 19p13.3, while its receptor is encoded by the AMHR2 gene on chromosome 12.AMH is activated by SOX9 in the Sertoli cells of the male fetus. Its expression inhibits the development of the female reproductive tract, or Müllerian ducts (paramesonephric ducts), in the male embryo, thereby arresting the development of fallopian tubes, uterus, and upper vagina.
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途径
- Negative Regulation of Hormone Secretion
抗原
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