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TTR 抗体

The 小鼠 单克隆 anti-TTR antibody (ABIN7833608) specifically detects TTR in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7833608
发货至: 中国
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北京 101111
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Quick Overview for TTR 抗体 (ABIN7833608)

抗原

See all TTR 抗体
TTR (Transthyretin (TTR))

适用

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宿主

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小鼠

克隆类型

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  • 87
单克隆

标记

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This TTR antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 原理

    Anti-Transthyretin 56-61, amyloid specific (mouse monoclonal)

    交叉反应 (详细)

    Human Transthyretin Amyloids
    Not reactive in: No confirmed exceptions from predicted reactivity are currently known

    纯化方法

    Affinity purified

    免疫原

    Recombinant protein corresponding to the Human wild type Transthyretin. GPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE The epitope has been mapped to residue 56-61

    亚型

    IgG1
  • 应用备注

    1:1000 (ELISA), 1:500 (IHC), 1:1000 (WB)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL sterile water to reconstitute to 1 mg/mL

    缓冲液

    Affinity purified in PBS pH 7.4.

    注意事项

    Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube

    储存条件

    4 °C

    储存方法

    Store lyophilized/reconstituted at 4°C, Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
  • 抗原

    TTR (Transthyretin (TTR))

    别名

    Transthyretin 56-61

    背景

    Transthyretin (TTR), formerly known as Prealbumin, is in vivo involved in the binding and transportation of the Thyroxin hormone and retinol-binding protein. Mutations in TTR are associated with familial amyloidotic polyneuropathy (FAP) which is a fatal disease characterized by amyloid depositions found in visceral organs including the heart, liver, and kidney. The wild type form of TTR is associated with a late onset amyloidosis denoted senile systemic amyloidosis, affecting around 10 % of the population above 80 years of age with depositions mainly found in the heart.Monoclonal IgG1 antibody. Amyloid specific for human Transthyretin. Detects the C-terminal fragment 49-127 frequently formed in vivo.

    分子量

    155

    途径

    Hormone Transport
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