TTR 抗体
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北京 101111
Quick Overview for TTR 抗体 (ABIN7833608)
抗原
See all TTR 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-Transthyretin 56-61, amyloid specific (mouse monoclonal)
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交叉反应 (详细)
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Human Transthyretin Amyloids
Not reactive in: No confirmed exceptions from predicted reactivity are currently known -
纯化方法
- Affinity purified
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免疫原
- Recombinant protein corresponding to the Human wild type Transthyretin. GPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE The epitope has been mapped to residue 56-61
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亚型
- IgG1
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应用备注
- 1:1000 (ELISA), 1:500 (IHC), 1:1000 (WB)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL sterile water to reconstitute to 1 mg/mL
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缓冲液
- Affinity purified in PBS pH 7.4.
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注意事项
- Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube
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储存条件
- 4 °C
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储存方法
- Store lyophilized/reconstituted at 4°C, Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
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- TTR (Transthyretin (TTR))
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别名
- Transthyretin 56-61
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背景
- Transthyretin (TTR), formerly known as Prealbumin, is in vivo involved in the binding and transportation of the Thyroxin hormone and retinol-binding protein. Mutations in TTR are associated with familial amyloidotic polyneuropathy (FAP) which is a fatal disease characterized by amyloid depositions found in visceral organs including the heart, liver, and kidney. The wild type form of TTR is associated with a late onset amyloidosis denoted senile systemic amyloidosis, affecting around 10 % of the population above 80 years of age with depositions mainly found in the heart.Monoclonal IgG1 antibody. Amyloid specific for human Transthyretin. Detects the C-terminal fragment 49-127 frequently formed in vivo.
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分子量
- 155
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途径
- Hormone Transport
抗原
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