SPA 抗体 (Agarose Beads)
Our Local Distributor
北京 101111
Quick Overview for SPA 抗体 (Agarose Beads) (ABIN7833390)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Anti-Staphylococcal Protein A, agarose-conjugated
-
交叉反应 （详细）
- Protein A from Staphylococcus aureus
-
纯化方法
- Immunogen affinity purified
-
免疫原
- Recombinant Protein A
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Immunogen affinity purified in PBS pH 7.2. Contains 0.075 % sodium azide, coupled to immunoprecipiation gel.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Do not freeze
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at +4-8°C. Do not freeze.
-
-
- SPA (Immunoglobulin G Binding Protein A (SPA))
-
别名
- Staphylococcal Protein A
-
背景
-
Background: Protein A is a surface protein of S. aureus which binds IgG molecules by their Fc region. In serum, the bacteria will bind IgG molecules in the wrong orientation on their surface, which hinders opsonization and phagocytosis. Mutants of S. aureus lacking protein A are more efficiently phagocytosed in vitro and mutants in infection models have diminished virulence. Due to its affinity for the Fc region of many mammalian immunoglobulins, protein A is considered a universal reagent in biochemistry and immunology.
Additional information: Antibodies were isolated from immune eggs, affinity purified on a protein A column and conjugated to N- hydroxysuccinimide (NHS)-activated agarose beads, Beads were washed extensively with after the blocking of the residual NHS sites
抗原
-
