CYP21A2 抗体 (AA 101-200) (Cy3)
Quick Overview for CYP21A2 抗体 (AA 101-200) (Cy3) (ABIN740358)
抗原
See all CYP21A2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 101-200
-
交叉反应
- 大鼠
-
预测反应
- Human,Mouse,Dog,Cow,Pig,Horse
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human CYP21
-
亚型
- IgG
-
-
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))
-
别名
- Cyp21
-
背景
-
Synonyms: Cytochrome P450 21, cytochrome P450, family 21, subfamily A, polypeptide 2, 21-OH, 21OHA, 21OHB, CA21H, CAH1, CHOLESTEROL 21-HYDROXYLASE, CPS1, CYP21, Cyp21-ps1, Cyp21a1, CYP21A2, Cyp21a2-ps, CYP21B, CYP21OH-A, MGC150536, MGC150537, MGC156449, Oh21-1, Oh21-2, P450C21, P450c21B, CYP21A2, CP21A_HUMAN.
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene, gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
-
基因ID
- 1589
-
途径
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
抗原
-