Recombinant CXCR6 抗体
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北京 101111
Quick Overview for Recombinant CXCR6 抗体 (ABIN7829682)
抗原
See all CXCR6 抗体抗体类型
片段
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CXCR6 antibody(2B3), IgG1 Chimeric mAb
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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亚型
- IgG1
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应用备注
- ELISA 1/5000-10000
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限制
- 仅限研究用
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状态
- Lyophilized
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).
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有效期
- 12 months
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- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
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别名
- CXCR6
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背景
- The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. [provided by RefSeq, Aug 2020]
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UniProt
- O00574
抗原
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