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AVEN 抗体 (AA 301-362) (FITC)

This anti-AVEN antibody is a 兔 多克隆 antibody detecting AVEN in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN740287
发货至: 中国

Quick Overview for AVEN 抗体 (AA 301-362) (FITC) (ABIN740287)

抗原

See all AVEN 抗体
AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))

适用

  • 46
  • 13
  • 6
  • 3

宿主

  • 43
  • 3

克隆类型

  • 41
  • 4
多克隆

标记

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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This AVEN antibody is conjugated to FITC

应用范围

  • 38
  • 19
  • 12
  • 12
  • 8
  • 7
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 9
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-362

    预测反应

    Human,Mouse,Rat,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human AVEN

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))

    别名

    Aven

    背景

    Synonyms: 1700013A01Rik, 1700056A21Rik, mAven L, mAven S, MGC124011, Apoptosis caspase activation inhibitor, Cell death regulator Aven, OTTMUSP00000016129, PDCD12, Programmed cell death 12, RP23-52C15.2, AVEN_HUMAN

    Background: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. AVEN is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9. It is thought that AVEN functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that AVEN impedes Apaf-1-mediated caspase activation. Higher levels of AVEN mRNA are seen in patients with acute leukemia than in control patients, suggesting that AVEN may be useful as a prognostic indicator in leukemia patients.

    基因ID

    57099
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