2B4 抗体
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北京 101111
Quick Overview for 2B4 抗体 (ABIN7828847)
抗原
See all 2B4 (CD244) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Purified Anti-Human CD244 Antibody[C1.7]
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纯化方法
- >98%, Protein A/G purified
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纯度
- >98 %
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免疫原
- Recombinant Human CD244 protein
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亚型
- IgG1, kappa
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应用备注
- FCM 2 μg/mL(0.5x106-1x106 cells)
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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有效期
- 12 months
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- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
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别名
- CD244
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背景
- 2B4,C9.1,CD244 antigen,CD244 Molecule,CD244 Molecule natural killer cell receptor 2B4,CD244 natural killer cell receptor 2B4,F730046O15Rik,Ly90,member 4,Natural killer cell activation-inducing ligand,NK cell activation inducing ligand,NK cell activation inducing ligand NAIL,NK cell type I receptor protein 2B4,Non-MHC restricted killing associated,OTTHUMP00000027884,p38,signaling lymphocytic activation molecule 4,SLAM family,h2B,SLAM family member,Natural killer cell receptor 2B,NKR2B,SLAMF,CD244,2B4,NAIL,NKR2B4,Nmrk,SLAMF4,h2B4,Natural killer cell receptor 2B4,NK cell activation-inducing ligand,SLAM family member 4,CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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UniProt
- Q9BZW8
抗原
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