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LY75/DEC-205 抗体

The 大鼠 单克隆 anti-LY75/DEC-205 antibody (Clone NLDC-145) (ABIN7828842) specifically detects LY75/DEC-205 in FACS. The antibody is reactive with 小鼠 samples.
产品编号 ABIN7828842
发货至: 中国
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Quick Overview for LY75/DEC-205 抗体 (ABIN7828842)

抗原

See all LY75/DEC-205 (LY75) 抗体
LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

适用

  • 70
  • 44
  • 8
  • 8
  • 2
小鼠

宿主

  • 51
  • 30
  • 13
  • 6
  • 1
  • 1
大鼠

克隆类型

  • 65
  • 32
  • 3
单克隆

标记

  • 45
  • 11
  • 9
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
This LY75/DEC-205 antibody is un-conjugated

应用范围

  • 37
  • 28
  • 27
  • 20
  • 17
  • 16
  • 13
  • 10
  • 4
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

NLDC-145
  • 原理

    AF/LE Purified Anti-Mouse CD205 Antibody[NLDC-145]

    纯化方法

    >98%, Protein A/G purified

    纯度

    >98 %

    免疫原

    Recombinant Mouse CD205 protein

    亚型

    IgG2a, kappa
  • 应用备注

    FCM 2 μg/mL(0.5x106-1x106 cells)

    限制

    仅限研究用
  • 浓度

    ≥ 1 mg/mL

    缓冲液

    Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

    储存液

    Without preservative

    注意事项

    This preparation contains no preservatives, thus it should be handled under aseptic conditions

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

    有效期

    12 months
  • 抗原

    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

    别名

    CD205

    背景

    Cd205,Ly75,DEC-205,Ly-75,CD205, also known as DEC-205, is a 205 kD integral membrane protein homologous to the macrophage mannose receptor. It is a type I cell surface protein that belong to the C-type lectin family. CD205 is expressed at high levels by dendritic cells and thymic epithelial cells. It is also expressed by a number of other cell types, such as B lymphocytes, macrophages, Langerhans cells, bone marrow stromal cells, granulocytes, epithelial cells of pulmonary airways, and the capillaries of the brain. CD205 is a novel endocytic receptor used by dendritic cells and thymic epithelial cells to direct captured antigens from the extracellular space to specialized antigen processing. It mediates antigen uptake and presentation and cross-presentation to T cells. It has been reported that CD205 acts as a recognition receptor for dying cells, potentially provides an important pathway for the uptake of self-antigen in the intrathymic environment, and is involved in peripheral tolerance. Antibody-mediated antigen-targeting via the DEC-205 receptor increases the efficiency of vaccination for T cell immunity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    UniProt

    Q60767
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