CD8 alpha 抗体
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北京 101111
Quick Overview for CD8 alpha 抗体 (ABIN7828709)
抗原
See all CD8 alpha (CD8A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- AF/LE Purified Anti-Rat Cd8a Antibody[OX-8]
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纯化方法
- >98%, Protein A/G purified
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纯度
- >98 %
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免疫原
- Recombinant Rat CD8a protein
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亚型
- IgG1, kappa
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应用备注
- FCM 2 μg/mL(0.5x106-1x106 cells)
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
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储存液
- Without preservative
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注意事项
- This preparation contains no preservatives, thus it should be handled under aseptic conditions
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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有效期
- 12 months
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- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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别名
- Cd8a
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背景
- T-lymphocyte differentiation antigen T8/Leu,MAL,T-cell surface glycoprotein CD8 alpha chain,T-lymphocyte differentiation antigen T8/Leu-2,Cd8a,CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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UniProt
- P07725
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途径
- TCR Signaling
抗原
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