Recombinant WHSC1L1 抗体
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北京 101111
Quick Overview for Recombinant WHSC1L1 抗体 (ABIN7828678)
抗原
See all WHSC1L1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant NSD3 Monoclonal Antibody
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纯化方法
- Protein A purified
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亚型
- IgG, kappa
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anti-Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1) antibody
WHSC1L1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1) (AA 1-645) antibodyWHSC1L1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1) (AA 1-270) antibodyWHSC1L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1) antibodyWHSC1L1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB245 unconjugated Recombinant Antibody
anti-Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1) (N-Term) antibodyWHSC1L1 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1) (AA 1-645) antibodyWHSC1L1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1) (AA 383-660) antibodyWHSC1L1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1) (AA 188-217), (N-Term) antibodyWHSC1L1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB12677 unconjugated
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应用备注
- WB 1:1000-1:3000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- WHSC1L1 (Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1))
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别名
- NSD3
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背景
- NSD,WHSC1L,NSD3,KMT3F,KMT3G,WHISTLE,WHSC1L1,pp14328,DC28,Wolf-Hirschhorn syndrome candidate 1-like protein 1 (WHSC1L1), also known as histone-lysine N-methyltransferase NSD3, is a SET domaincontaining histone methyltransferase protein that methylates histone H3 on lysine 4 (H3K4me) and lysine 27 (H3K27me) (1). Methylation of histone H3 lysine 4 is associated with transcriptional activation, while methylation of histone H3 lysine 27 is associated with transcriptional repression. WHSC1L1 can function as an oncogene or a tumor suppressor protein, depending on cell context, and has been shown to regulate expression of a number of genes associated with cell cycle (2). Amplification and/or increased expression of WHSC1L1 in breast, lung, and liver cancer increases growth and survival, and is associated with poor prognosis (2-5). In addition, the NSD3 gene has been found fused with the nuclear pore complex protein NUP98 gene in acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL), and fused with the NUT gene in NUT midline carcinomas (6-10). Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 162 kDa
Observed MW: 90 kDa The actual band is not consistent with the expectation.
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UniProt
- Q9BZ95
抗原
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