Recombinant WT1 抗体
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北京 101111
Quick Overview for Recombinant WT1 抗体 (ABIN7828676)
抗原
See all WT1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant WT1 Monoclonal Antibody
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纯化方法
- Protein A purified
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亚型
- IgG, kappa
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应用备注
- WB 1:2000-1:10000,IHC 1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- WT1 (Wilms Tumor 1 (WT1))
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别名
- WT1
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背景
- AWT,FWT,NPHS,EWS-WT,WIT,WT1,AWT1,EWS-WT1,GUD,NPHS4,WAGR,WIT-2,WT33,FWT1,Wilms Tumor,Wilms tumor 1,Wilms' tumor gene,Wilms tumor protein,Wilms' tumor protein,WIT 2,WIT2,WT,WT 1,WIT 2, WT 1,AWT1,FWT1,GUD,NPHS4,WAGR,Wilms tumor 1,Wilms Tumor,Wilms tumor protein,Wilms' tumor gene,Wilms' tumor protein,WIT2,WT,WT1,WT1,WT33,Wilms' Tumor protein (WT1) is a transcription factor named from Wilms' Tumor 1, an embryonal malignancy of the kidneys that is caused by mutations in the WT1 gene. It is highly important in development, particularly of the genitourinary system, and mutations and dysregulation of expression of WT1 result in a variety of syndromes affecting the genitourinary system and other tissues.WT1 has a myriad of biological functions and a host of interacting partners and target genes. It can behave as a transcriptional activator, or a repressor, and can act as an oncogene or a tumor suppressor. It exerts influence over the epigenetic landscape, and also has post translational influence of gene expression through RNA interactions. The diverse biological roles of WT1 have been attributed to the existence of multiple isoforms and post translation modifications of the protein. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 49 kDa
Observed MW: 52 kDa The actual band is not consistent with the expectation.
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UniProt
- P19544
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途径
- Tube Formation
抗原
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