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Recombinant WT1 抗体

The 兔 单克隆 anti-WT1 antibody is suitable to detect WT1 in samples from 人, 大鼠 和 小鼠. It has been validated for IHC 和 WB.
产品编号 ABIN7828676
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant WT1 抗体 (ABIN7828676)

抗原

See all WT1 抗体
WT1 (Wilms Tumor 1 (WT1))

抗体类型

Recombinant Antibody

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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单克隆

标记

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This WT1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB)

克隆位点

A742
  • 原理

    Recombinant WT1 Monoclonal Antibody

    纯化方法

    Protein A purified

    亚型

    IgG, kappa
  • 应用备注

    WB 1:2000-1:10000,IHC 1:100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    WT1 (Wilms Tumor 1 (WT1))

    别名

    WT1

    背景

    AWT,FWT,NPHS,EWS-WT,WIT,WT1,AWT1,EWS-WT1,GUD,NPHS4,WAGR,WIT-2,WT33,FWT1,Wilms Tumor,Wilms tumor 1,Wilms' tumor gene,Wilms tumor protein,Wilms' tumor protein,WIT 2,WIT2,WT,WT 1,WIT 2, WT 1,AWT1,FWT1,GUD,NPHS4,WAGR,Wilms tumor 1,Wilms Tumor,Wilms tumor protein,Wilms' tumor gene,Wilms' tumor protein,WIT2,WT,WT1,WT1,WT33,Wilms' Tumor protein (WT1) is a transcription factor named from Wilms' Tumor 1, an embryonal malignancy of the kidneys that is caused by mutations in the WT1 gene. It is highly important in development, particularly of the genitourinary system, and mutations and dysregulation of expression of WT1 result in a variety of syndromes affecting the genitourinary system and other tissues.WT1 has a myriad of biological functions and a host of interacting partners and target genes. It can behave as a transcriptional activator, or a repressor, and can act as an oncogene or a tumor suppressor. It exerts influence over the epigenetic landscape, and also has post translational influence of gene expression through RNA interactions. The diverse biological roles of WT1 have been attributed to the existence of multiple isoforms and post translation modifications of the protein. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 49 kDa

    Observed MW: 52 kDa The actual band is not consistent with the expectation.

    UniProt

    P19544

    途径

    Tube Formation
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