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Recombinant VWF 抗体

The 兔 单克隆 anti-VWF antibody (Clone A683) (ABIN7828674) specifically detects VWF in IHC 和 WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7828674
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant VWF 抗体 (ABIN7828674)

抗原

See all VWF 抗体
VWF (Von Willebrand Factor (VWF))

抗体类型

Recombinant Antibody

适用

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人, 小鼠

宿主

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克隆类型

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  • 2
单克隆

标记

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This VWF antibody is un-conjugated

应用范围

  • 146
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Immunohistochemistry (IHC), Western Blotting (WB)

克隆位点

A683
  • 原理

    Recombinant Von Willebrand Factor Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human Von Willebrand Factor fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:5000-1:10000,IHC 1:100-1:1000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    VWF (Von Willebrand Factor (VWF))

    别名

    Von Willebrand Factor

    背景

    F8VWF,VWD,von Willebrand factor,von Willebrand antigen II,Vwf,VWF (Von Willebrand factor) is a multimeric plasma glycoprotein that promotes adhesion of platelets to sites of vascular injury. Mature circulating VWF is made up of disulfide-bonded multimers that are in a complex with factor VIII. VWF is stored in secretory Weibel-Palade bodies in endothelial cells. It is synthesized as a large precursor protein and undergoes extensive posttranslational modifications including dimerization in the endoplasmic reticulum followed by cleavage of the pro-peptide and multimerization in the Golgi apparatus. VWF is important in hemostasis, and genetic defects in the structure and modification of VWF can cause von Willebrand disease (VWD), the most common congenital bleeding disorder in humans. Alternatively, increased levels of VWF have been shown to be involved in acute coronary thrombosis and are a clinical risk marker for atherosclerosis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 309 kDa

    Observed MW: 309 kDa

    UniProt

    Q8CIZ8
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