Recombinant VTCN1 抗体
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北京 101111
Quick Overview for Recombinant VTCN1 抗体 (ABIN7828665)
抗原
See all VTCN1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant B7-H4 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human B7-H4 fragment
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亚型
- IgG, kappa
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anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 50-100) antibody
VTCN1 适用: 人 FACS, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 34-147) antibodyVTCN1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) antibodyVTCN1 适用: 人 WB, IHC, FACS, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal B7H4-1788 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 153-241) antibodyVTCN1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (Internal Region) antibodyVerified VTCN1 适用: 人 WB, FACS, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) antibodyVTCN1 适用: 人 IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal H74 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) antibodyVTCN1 适用: 人 IHC, FACS, ELISA, IF, Coat, StM 宿主: 兔 Monoclonal B7H4-2652R unconjugated Recombinant Antibody
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 25-259) antibodyVTCN1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 3A9C12 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 26-258) antibodyVTCN1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 34-147) antibodyVTCN1 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal 6# unconjugated
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应用备注
- WB 1:500-1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
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别名
- B7-H4
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背景
- B7S,PRO,UNQ,VTCN,B7-H,VCTN,B7h,VTCN1,B7-H4,B7H4,B7S1,B7X,B7h.5,PRO1291,VCTN1,UNQ659,B7H4T-cell costimulatory molecule B7x,B7S1VCTN1,B7XPRO1291,FLJ22418,Immune costimulatory protein B7-H4,Protein B7S1,T cell costimulatory molecule B7x,V-set domain containing T cell activation inhibitor 1,V-set domain-containing T-cell activation inhibitor 1,B7 homolog 4 (B7-H4), also known as VTCN1, is a member of the B7 family of cell surface ligands that regulate T cell activation and immune responses. B7-H4 protein contains two extracellular Ig-like V-type domains, a transmembrane domain, and a short, two amino acid intracellular domain. The B7-H4 protein is shown to inhibit T cell activation, proliferation, and cytokine production. Although B7-H4 mRNA is widely expressed, B7-H4 protein is restricted to antigen presenting cells and B cells. The B7-H4 protein is also found in several tumor types, including ovarian cancer and breast cancer. Research studies indicate that B7-H4 protein is present on the surface of ovarian tumor cells, and that targeted inhibition of B7-H4 using recombinant antibodies restores T cell activation pathways. These studies suggest some potential therapeutic value in blocking B7-H4 function and restoring T cell function in cancer patients. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 20, 31 kDa
Observed MW: 45, 65 kDa The actual band is not consistent with the expectation.
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UniProt
- Q7Z7D3
抗原
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