Recombinant UBE2K 抗体
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北京 101111
Quick Overview for Recombinant UBE2K 抗体 (ABIN7828658)
抗原
See all UBE2K 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant HIP2/LIG Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human HIP2/LIG fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
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别名
- HIP2/LIG
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背景
- HIP,UBC,UBE2K,E2-25K,HIP2,HYPG,LIG,UBC1,HIP-2,Huntingtin-Interacting Protein 2,Ubiquitin Carrier Protein,Ubiquitin-Conjugating Enzyme E2 K,Ubiquitin-Conjugating Enzyme E2(25K),Ubiquitin-Conjugating Enzyme E2-25 kDa,Ubiquitin-Conjugating Enzyme E2-25K,Ubiquitin-Protein Ligase,Huntingtin-interacting protein 2 (HIP2/LIG), is a E2 ubiquitin-conjugating enzyme, which accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, HIP2/LIG catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, while it does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Moreover, HIP2/LIG mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 22 kDa
Observed MW: 22 kDa
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UniProt
- P61086
抗原
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