Recombinant TTR 抗体
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北京 101111
Quick Overview for Recombinant TTR 抗体 (ABIN7828640)
抗原
See all TTR 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Prealbumin/Transthyretin Monoclonal Antibody
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纯化方法
- Protein A purified
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亚型
- IgG, kappa
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anti-Transthyretin (TTR) (AA 21-147) antibody
TTR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transthyretin (TTR) (AA 1-147) antibodyTTR 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2E10C5 unconjugated
anti-Transthyretin (TTR) (AA 20-147) antibodyTTR 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Transthyretin (TTR) (AA 21-147) antibodyTTR 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Transthyretin (TTR) (AA 21-150) antibodyTTR 适用: Pig WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Transthyretin (TTR) antibodyTTR 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Transthyretin (TTR) (AA 21-147) antibodyTTR 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Transthyretin (TTR) antibodyTTR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transthyretin (TTR) antibodyTTR 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-Transthyretin (TTR) (C-Term) antibodyTTR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000,IHC 1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- TTR (Transthyretin (TTR))
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别名
- Prealbumin/Transthyretin
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背景
- HEL,HsT,TTR,CTS,CTS1,HEL111,HsT2651,PALB,TBPA,ATTR,Prealbumin,Transthyretin,Amyloid polyneuropathy,Amyloidosis I,Carpal tunnel syndrome 1,Dysprealbuminemic euthyroidal hyperthyroxinemia,Dystransthyretinemic hyperthyroxinemia,Epididymis luminal protein 111,Prealbumin amyloidosis type I,Prealbumin Thyroxine-binding,Senile systemic amyloidosis,Thyroxine binding prealbumin,Transthyretin,TTR,TTHY,TTR protein,Transthyretin (TTR) is a highly conserved homotetremric protein that is synthesized in the liver and choroid plexus of the brain. TTR wasoriginally discovered as a protein found in human plasma and cerebrospinal fluid (CSF). TTR transports thyroid hormones (TH) and retinol bybinding to retinol-binding protein. Although TTR is synthesized in the liver and choroid plexus, TTR is detected in blood plasma andcerebrospinal fluid migrating as monomers, dimers, and tetramers. Beyond its function as a carrier protein of TH and retinol in plasma andCSF, several additional TTR functions have been described, including proteolytic cleavage of specific substrates like apolipoprotein,neuropeptide Y (NPY), and APP. These neuronal substrates suggest a functional role for TTR in the central nervous system. Consistent witha CNS function, TTR null mice exhibit memory impairments and altered sensorimotor behavior). TTR may also be linked to neurodegenerativedisease: TTR levels in Alzheimer's disease (AD) patients are negatively correlated with disease progression, and a protective role for TTR, atleast in AD mouse models, has been described. TTR itself may play a more direct role in disease as gain-of-function mutations in TTR causethe protein to misfold and aggregate into amyloid fibrils, contributing to autosomal dominant hereditary amyloidosis in diseases such as familialamyloid polyneuropathy, familial amyloid cardiomyopathy, and familial leptomeningeal amyloidosis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 16 kDa
Observed MW: 35 kDa The actual band is not consistent with the expectation.
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UniProt
- P02766
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途径
- Hormone Transport
抗原
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