Recombinant TBL1XR1 抗体
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Quick Overview for Recombinant TBL1XR1 抗体 (ABIN7828633)
抗原
See all TBL1XR1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant TBLR1/TBL1XR1 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human TBLR1/TBL1XR1 fragment
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亚型
- IgG, kappa
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anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) (AA 81-178) antibody
TBL1XR1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G7 unconjugated
anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) (AA 1-180) antibodyTBL1XR1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) (AA 1-180) antibodyTBL1XR1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) antibodyTBL1XR1 适用: 人, 小鼠 WB, IHC, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) antibodyKD Validated TBL1XR1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB5895 unconjugated
anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) antibodyTBL1XR1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) antibodyTBL1XR1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4935 unconjugated Recombinant Antibody
anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) (AA 231-330) antibodyTBL1XR1 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) (C-Term) antibodyTBL1XR1 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, Pig, 小鸡, 豚鼠, 马, 兔, Bat, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) (C-Term) antibodyTBL1XR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:2000-1:5000,IHC 1:50-1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))
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别名
- TBLR1/TBL1XR1
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背景
- MRD,IRA,TBLR,TBL1XR,TBL1XR1,C21,DC42,IRA1,MRD41,TBLR1,TBL1-related protein 1 (TBLR1/TBL1XR1) and Transducing β-like protein 1 (TBL1X/TBL1) were originally identified as subunits of the co-repressor silencing mediator for retinoic and thyroid hormone receptor (SMRT) and nuclear receptor co-repressor (NCoR) complexes. These two factors are required for the exchange of co-repressor complexes for co-activators by acting as adaptors to recruit the ubiquitin/proteasome machinery that degrades the co-repressor proteins during ligand mediated activation of transcription. Co-factor exchange driven by TBLR1/TBL1XR1 and TBL1X/TBL1 appears to be the mechanism by which c-Jun and NF-κB mediated transcription is activated and is therefore likely to be the mechanism employed by other signal-dependent transcription factors as well. In addition, both TBLR1/TBL1XR1 and TBL1X/TBL1 have essential roles in regulating the Wnt-signaling pathway by recruiting β-catenin to Wnt target genes to activate transcription. Depletion of TBLR1/TBL1XR1 significantly inhibited Wnt-beta-catenin- induced gene expression and oncogenic growth in vitro and in vivo. Research studies have shown that upregulation of TBLR1/TBL1XR1 is observed in a variety of solid tumors, and is correlated with advanced tumor stage, metastasis and poor prognosis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 56 kDa
Observed MW: 60 kDa The actual band is not consistent with the expectation.
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UniProt
- Q9BZK7
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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