Recombinant TYMS 抗体
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北京 101111
Quick Overview for Recombinant TYMS 抗体 (ABIN7828623)
抗原
See all TYMS 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Thymidylate Synthase Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human Thymidylate Synthase fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:2000,IF 1:50,FCM 1:50-1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- TYMS (Thymidylate Synthetase (TYMS))
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别名
- Thymidylate Synthase
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背景
- HST,OK/SW-cl,TYMS,HST422,TMS,TS,thymidylate synthase,OK/SW-cl.29,HST422,thymidylate synthase,TMS,thymidylate synthetase,Thymidylate synthase is a homodimer composed of two 30 kDa subunits, which catalyze the methylation of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), an essential step in the formation of thymine nucleotides. Thymidylate synthase is an intracellular enzyme that provides the sole de novo source of thymidylate, making it a required enzyme in DNA biosynthesis with activity highest in proliferating cells. Being the exclusive source of dTMP, investigators have concluded that TS is also an important target for anticancer agents such as 5-fluorouracil (5-FU). 5-FU acts as a TS inhibitor and is active against solid tumors such as colon, breast, head, and neck. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 36 kDa
Observed MW: 36 kDa
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UniProt
- P04818
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途径
- Mitotic G1-G1/S Phases
抗原
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