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Recombinant TYMS 抗体

The 兔 单克隆 anti-TYMS antibody (Clone A524) (ABIN7828623) specifically detects TYMS in IF, WB 和 FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7828623
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant TYMS 抗体 (ABIN7828623)

抗原

See all TYMS 抗体
TYMS (Thymidylate Synthetase (TYMS))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

  • 65
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克隆类型

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单克隆

标记

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This TYMS antibody is un-conjugated

应用范围

  • 65
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Immunofluorescence (IF), Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

A524
  • 原理

    Recombinant Thymidylate Synthase Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human Thymidylate Synthase fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:2000,IF 1:50,FCM 1:50-1:100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    TYMS (Thymidylate Synthetase (TYMS))

    别名

    Thymidylate Synthase

    背景

    HST,OK/SW-cl,TYMS,HST422,TMS,TS,thymidylate synthase,OK/SW-cl.29,HST422,thymidylate synthase,TMS,thymidylate synthetase,Thymidylate synthase is a homodimer composed of two 30 kDa subunits, which catalyze the methylation of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), an essential step in the formation of thymine nucleotides. Thymidylate synthase is an intracellular enzyme that provides the sole de novo source of thymidylate, making it a required enzyme in DNA biosynthesis with activity highest in proliferating cells. Being the exclusive source of dTMP, investigators have concluded that TS is also an important target for anticancer agents such as 5-fluorouracil (5-FU). 5-FU acts as a TS inhibitor and is active against solid tumors such as colon, breast, head, and neck. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 36 kDa

    Observed MW: 36 kDa

    UniProt

    P04818

    途径

    Mitotic G1-G1/S Phases
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