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Recombinant SV2A 抗体

This 兔 单克隆 antibody specifically detects SV2A in WB 和 IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7828606
发货至: 中国
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Quick Overview for Recombinant SV2A 抗体 (ABIN7828606)

抗原

See all SV2A 抗体
SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

抗体类型

Recombinant Antibody

适用

  • 47
  • 22
  • 21
  • 5
  • 5
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  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 43
  • 2
  • 1
  • 1
  • 1

克隆类型

  • 46
  • 2
单克隆

标记

  • 18
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This SV2A antibody is un-conjugated

应用范围

  • 18
  • 14
  • 13
  • 12
  • 8
  • 4
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A710
  • 原理

    Recombinant SV2A Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000,IHC 1:500-1:1000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

    别名

    SV2A

    背景

    KIAA,PSEC,SV2,SV2A,KIAA0736,PSEC0174,SV2s are a family of synaptic vesicle proteins expressed in both neurons and endocrine cells. SV2s function in the regulation of synaptic vesicle traffic, cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation and the facilitation of synaptic transmission. There are three isoforms of SV2: SV2A, SV2B and SV2C. Each of these isoforms are structured similarly but expressed varyingly. SV2C, a minor isoform of SV2, expressed in a small subset of neurons located within the basal forebrain, midbrain and brainstem. SV2B, a major isoform of SV2 is expressed more abundantly, although rarely without the coexpression of SV2A. SV2A, the other major isoform of SV2 is the most widely expressed. SV2A is located in the presynaptic nerve terminals of almost every neuron throughout the nervous system. In addition, it is also located in most neuroendocrine secretory granules. SV2A has been identified as a critical protein for proper function of the central nervous system and has been linked to the physiopathology of epilepsy. In addition to the epileptic affects of this protein, mutations in it have also been seen to result in schizophrenia. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 83 kDa

    Observed MW: 100 kDa The actual band is not consistent with the expectation.

    UniProt

    Q7L0J3
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