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Recombinant SIRT6 抗体

The 兔 单克隆 anti-SIRT6 antibody is suitable to detect SIRT6 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN7828568
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant SIRT6 抗体 (ABIN7828568)

抗原

See all SIRT6 抗体
SIRT6 (Sirtuin 6 (SIRT6))

抗体类型

Recombinant Antibody

适用

  • 89
  • 32
  • 18
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 86
  • 12
  • 2

克隆类型

  • 80
  • 20
单克隆

标记

  • 57
  • 11
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIRT6 antibody is un-conjugated

应用范围

  • 79
  • 35
  • 31
  • 14
  • 14
  • 12
  • 11
  • 7
  • 7
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB)

克隆位点

A547
  • 原理

    Recombinant SIRT6 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human SIRT6 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:1000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    SIRT6 (Sirtuin 6 (SIRT6))

    别名

    SIRT6

    背景

    SIRT,SIR2L,sirtuin,SIR2L6,SIRT6,sirtuin 6,SirT6, a mammalian homolog of Sir2, is a nuclear, chromatin-associated protein that promotes the normal maintenance of genome integrity mediated by the base excision repair (BER) pathway. The BER pathway repairs single-stranded DNA lesions that arise spontaneously from endogenous alkylation, oxidation, and deamination events. SirT6 deficient mice show increased sensitivity to DNA-damaging agents, including the alkylating agents MMS and H2O2. In addition, these mice show genome instability with increased frequency of fragmented chromosomes, detached centromeres, and gaps. SirT6 may regulate the BER pathway by deacetylating DNA Polβ or other core components of the pathway. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 39 kDa

    Observed MW: 42 kDa The actual band is not consistent with the expectation.

    UniProt

    Q8N6T7
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