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Recombinant SETD1A 抗体

The 兔 单克隆 anti-SETD1A antibody is suitable to detect SETD1A in samples from 人, 小鼠 和 大鼠. It has been validated for IHC, IF 和 FACS.
产品编号 ABIN7828559
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant SETD1A 抗体 (ABIN7828559)

抗原

See all SETD1A 抗体
SETD1A (SET Domain Containing 1A (SETD1A))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This SETD1A antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

A256
  • 原理

    Recombinant SETD1A Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human SETD1A fragment

    亚型

    IgG, kappa
  • 应用备注

    IHC 1:50-1:100,IF 1:100-1:500,FCM 1:50-1:100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    SETD1A (SET Domain Containing 1A (SETD1A))

    别名

    SETD1A

    背景

    Set,KIAA,Set1,KMT2F,Set1A,SETD1A,KIAA0339,Histone-lysine N-methyltransferase SETD1A,hSET1A,KMT2F,Lysine N methyltransferase 2F,Lysine N-methyltransferase 2F,SET domain containing 1A,SET domain containing protein 1A,SET domain-containing protein 1A,SET1,Set1 Ash2 histone methyltransferase complex subunit SET1,Set1/Ash2 histone methyltransferase complex subunit SET1,SET1A,hSET1 is a component of the histone methyltransferase (HMT) complex, which is a member of the COMPASS family, has H3K4 methyltransferase activity, and is closely related to development and tumors. hSET1 can produce mono-, di- and Trimethylation at lys4 (K4) on histone H3. This activity is blocked by the pre-methylation of the transcription repressor K9, indicating that the SET1/ASH2 complex can cause crosstalk between K9 methylation and K4 methylation. SET1 protein may play a role in synaptic function and neuron development. In addition, hSET1 protein can affect the proliferation and apoptosis of leukemia cells, and promote differentiation into neutrophils, providing new ideas for the treatment of leukemia and other cancers. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    UniProt

    O15047
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