Recombinant RUNX3 抗体
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北京 101111
Quick Overview for Recombinant RUNX3 抗体 (ABIN7828537)
抗原
See all RUNX3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant RUNX3 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human RUNX3 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:1000,IP 1:25-1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
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别名
- RUNX3
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背景
- AML,RUNX,CBFA,Oncogene AML,Core-binding factor subunit alpha,Runt-related transcription factor,PEBP2A,RUNX3,AML2,CBFA3,PEBP2aC,Acute myeloid leukemia 2 protein,Core-binding factor subunit alpha-3,Oncogene AML-2,Runt-related transcription factor 3,PEBP2A3,RUNX3 is a member of the Runt family of transcription factors, playing an important role in the suppression of gastric epithelium cell proliferation, dorsal root ganglia neurogenesis, and T cell differentiation. RUNX3 is also involved in Caspase-3-dependent apoptosis. Protein complexes containing RUNX3 and various transcription factors, such as Smads or β-catenin/TCF4, have tumor suppressor activity and regulate downstream target gene transcription. While typically localized to the nucleus, RUNX3 can be tyrosine phosphorylated and located in the cytoplasm of many cancer cells. This mislocalization of RUNX3 abolishes its tumor suppressor function and contributes to tumorigenesis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 46 kDa
Observed MW: 44-46 kDa The actual band is not consistent with the expectation.
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UniProt
- Q13761
抗原
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