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Recombinant Retinoid X Receptor alpha 抗体

The 兔 单克隆 anti-Retinoid X Receptor alpha antibody (Clone A659) (ABIN7828527) specifically detects Retinoid X Receptor alpha in WB 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7828527
发货至: 中国
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Quick Overview for Recombinant Retinoid X Receptor alpha 抗体 (ABIN7828527)

抗原

See all Retinoid X Receptor alpha (RXRA) 抗体
Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

抗体类型

Recombinant Antibody

适用

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宿主

  • 66
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克隆类型

  • 40
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单克隆

标记

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This Retinoid X Receptor alpha antibody is un-conjugated

应用范围

  • 60
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Western Blotting (WB), Immunofluorescence (IF)

克隆位点

A659
  • 原理

    Recombinant RXRA Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human RXRA fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000,IF 1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

    别名

    RXRA

    背景

    NR2B,NR2B1,RXRA,Retinoid X receptor alpha,Retinoid X receptor α (RXRA) is the founding RXR family member and is predominantly expressed in the liver, kidney, epidermis, intestine, and a variety of tissues. Knockout of the murine rxrα gene results in embryonic lethality tentatively due to myocardial hypoplasia, which demonstrates the importance of RXRA in retinoid signalingin vivo. Biochemical evidence suggests that RXRA transcriptional activity is post-translationally regulated through the Ras-Raf-MAPK signaling cascade. MAPK-dependent phosphorylation of RXRα directly abrogates the ability of RXRA to associate with nuclear receptor coactivators. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 51 kDa

    Observed MW: 56 kDa The actual band is not consistent with the expectation.

    UniProt

    P19793

    途径

    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C
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