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Recombinant RAG2 抗体

The 兔 单克隆 anti-RAG2 antibody (Clone A350) (ABIN7828521) specifically detects RAG2 in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7828521
发货至: 中国
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Quick Overview for Recombinant RAG2 抗体 (ABIN7828521)

抗原

See all RAG2 抗体
RAG2 (Recombination Activating Gene 2 (RAG2))

抗体类型

Recombinant Antibody

适用

  • 47
  • 14
  • 13
  • 2
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  • 1
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  • 1
  • 1
人, 小鼠

宿主

  • 41
  • 7

克隆类型

  • 43
  • 5
单克隆

标记

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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This RAG2 antibody is un-conjugated

应用范围

  • 21
  • 14
  • 13
  • 13
  • 7
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
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Western Blotting (WB)

克隆位点

A350
  • 原理

    Recombinant RAG2 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human RAG2 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000-1:10000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    RAG2 (Recombination Activating Gene 2 (RAG2))

    别名

    RAG2

    背景

    RAG,RAG2,RAG-2,recombination activating 2,recombination activating gene 2,Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends. The chromatin structure plays an essential role in the V(D)J recombination reactions and the presence of histone H3 trimethylated at 'Lys-4' (H3K4me3) stimulates both the nicking and haipinning steps. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 62 kDa

    Observed MW: 62 kDa

    UniProt

    P55895

    途径

    Chromatin Binding, Production of Molecular Mediator of Immune Response
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