Recombinant QKI 抗体
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北京 101111
Quick Overview for Recombinant QKI 抗体 (ABIN7828501)
抗原
See all QKI 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant QKI Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human QKI fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:3000,IF 1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- QKI (Protein Quaking (QKI))
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别名
- QKI
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背景
- QKI,Hqk,QK,QK1,QK3,hqkI,HKQ,QKI is a member of the signal transduction and activator of RNA (STAR) protein family of RNA-binding proteins. Mutations in the mouse Qki locus results in impaired myelin formation resulting in tremors. QKI proteins exist as homodimers, and disruption of the dimerization process is lethal in mice. QKI exists in different isoforms that differ in their C-terminus, resulting in unique subcellular localizations. The nuclear isoform of QKI, QKI-5, is involved in regulation of alternative splicing of MAG mRNA, which encodes for a protein important for myelin sheath formation and maintenance. QKI has also been implicated in schizophrenia and oligodendrocyte differentiation. QKI can function as a tumor suppressor, as it is regulated by p53 to stabilize miRNAs that regulate TGF-β signaling. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 38 kDa
Observed MW: 38 kDa
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UniProt
- Q96PU8
抗原
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