Recombinant ARIH2 抗体
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北京 101111
Quick Overview for Recombinant ARIH2 抗体 (ABIN7828494)
抗原
See all ARIH2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant TRIAD1 Monoclonal Antibody
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纯化方法
- Protein A purified
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亚型
- IgG, kappa
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anti-protein ariadne-2 homolog (ARIH2) (AA 43-360) antibody
ARIH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-protein ariadne-2 homolog (ARIH2) antibodyARIH2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-protein ariadne-2 homolog (ARIH2) (AA 1-493) antibodyARIH2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-protein ariadne-2 homolog (ARIH2) (C-Term) antibodyARIH2 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-protein ariadne-2 homolog (ARIH2) (C-Term) antibodyVerified ARIH2 适用: 人, 小鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-protein ariadne-2 homolog (ARIH2) antibodyKD Validated ARIH2 适用: 人 WB 宿主: 小鼠 Monoclonal 24GB8000 unconjugated
anti-protein ariadne-2 homolog (ARIH2) (N-Term) antibodyARIH2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-protein ariadne-2 homolog (ARIH2) (N-Term) antibodyARIH2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-protein ariadne-2 homolog (ARIH2) (C-Term) antibodyARIH2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-protein ariadne-2 homolog (ARIH2) (N-Term) antibodyARIH2 适用: 人, 小鼠, 大鼠, 犬, Cow, 非洲爪蟾, 小鸡 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- ARIH2 (protein ariadne-2 homolog (ARIH2))
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别名
- TRIAD1
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背景
- ARI,ARIH,TRIAD,ARI2,TRIAD1,ARIH2,HT005,all trans retinoic acid inducible RING finger,Ari 2,Ari-2,Ariadne 2,Ariadne 2 protein homolog,ariadne homolog 2,ariadne homolog 2 (Drosophila),Ariadne RBR E3 ubiquitin protein ligase 2,ARIH 2,E3 ubiquitin protein ligase ARIH2,E3 ubiquitin-protein ligase ARIH2,protein ariadne 2 homolog,Protein ariadne-2 homolog,Triad 1,Triad1 protein,UIP48,The E3 ubiquitin-protein ligase ARIH2 (TRIAD1) is an Ariadne subfamily ligase involved in the polyubiquitination of proteins designated for proteasomal degradation. The TRIAD1 nuclear protein contains an amino-terminal acidic region, a pair of RING fingers, two carboxyl terminal coiled coil domains and a novel C6HC DRIL/IBR domain located between the RING fingers. Together, the paired RING fingers and DRIL/IBR domain form a highly conserved TRIAD (two RING fingers and DRIL) domain. Research studies suggest that TRIAD1 mediates both Lys48 and Lys63 protein polyubiquitination and acts as a negative regulator of myelopoiesis. TRIAD1 ubiquitin ligase inhibits myeloid cell proliferation by mediating protein ubiquitination through the ubiquitin-conjugating enzymes UbcH7 and UbcH13. Experimental deletion of TRIAD1 in mice has a lethal effect, leading to death at the embryonic stage or later due to a severe, multi-organ inflammatory response. Results indicate that TRIAD1 binds IκBβ in dendritic cells and promotes the degradation of the NF-κB inhibitor. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 58 kDa
Observed MW: 58 kDa
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UniProt
- O95376
抗原
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