Recombinant PCGF5 抗体
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北京 101111
Quick Overview for Recombinant PCGF5 抗体 (ABIN7828467)
抗原
See all PCGF5 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant PCGF5 Monoclonal Antibody
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纯化方法
- Protein A purified
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亚型
- IgG, kappa
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应用备注
- WB 1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- PCGF5 (Polycomb Group Ring Finger 5 (PCGF5))
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别名
- PCGF5
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背景
- RNF,Pcgf,RNF159,PCGF5,PCGF5 is the omponent of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.Within the PRC1-like complex, PCGF5 regulates RNF2 ubiquitin ligase activity. PCGF5 plays a redundant role with PCGF3 as part of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 30 kDa
Observed MW: 30 kDa
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UniProt
- Q86SE9
抗原
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