Recombinant PLAG1 抗体
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北京 101111
Quick Overview for Recombinant PLAG1 抗体 (ABIN7828465)
抗原
See all PLAG1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant PLAG1 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human PLAG1 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:5000-1:10000,IHC 1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))
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别名
- PLAG1
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背景
- ZNF,Zinc finger protein PLAG,Pleiomorphic adenoma gene,FGFR1/PLAG1 fusion variant,PLAG,COL1A2/PLAG1 fusion,FGFR1/PLAG1 fusion variant 3,Pleiomorphic adenoma gene 1,Pleiomorphic adenoma gene 1 protein,PSA,SGPA,Zinc finger protein PLAG1,ZNF912,PLAG1,PSA,SGPA,Pleiomorphic adenoma gene 1 protein (PLAG1) is a transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation. When PLAG1 overexpression in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. PLAG1 ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. PLAG1 overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. PLAG1 cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 56 kDa
Observed MW: 56 kDa
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UniProt
- Q6DJT9
抗原
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