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Recombinant PLAG1 抗体

This 兔 单克隆 antibody specifically detects PLAG1 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7828465
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant PLAG1 抗体 (ABIN7828465)

抗原

See all PLAG1 抗体
PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

  • 52
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克隆类型

  • 53
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单克隆

标记

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This PLAG1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A660
  • 原理

    Recombinant PLAG1 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human PLAG1 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:5000-1:10000,IHC 1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

    别名

    PLAG1

    背景

    ZNF,Zinc finger protein PLAG,Pleiomorphic adenoma gene,FGFR1/PLAG1 fusion variant,PLAG,COL1A2/PLAG1 fusion,FGFR1/PLAG1 fusion variant 3,Pleiomorphic adenoma gene 1,Pleiomorphic adenoma gene 1 protein,PSA,SGPA,Zinc finger protein PLAG1,ZNF912,PLAG1,PSA,SGPA,Pleiomorphic adenoma gene 1 protein (PLAG1) is a transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation. When PLAG1 overexpression in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. PLAG1 ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. PLAG1 overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. PLAG1 cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 56 kDa

    Observed MW: 56 kDa

    UniProt

    Q6DJT9
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