Recombinant PHF8 抗体
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北京 101111
Quick Overview for Recombinant PHF8 抗体 (ABIN7828452)
抗原
See all PHF8 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant PHF8 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human PHF8 fragment
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亚型
- IgG, kappa
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anti-PHD Finger Protein 8 (PHF8) antibody
PHF8 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB945 unconjugated Recombinant Antibody
anti-PHD Finger Protein 8 (PHF8) antibodyPHF8 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-PHD Finger Protein 8 (PHF8) (AA 650-700) antibodyPHF8 适用: 人, 小鼠, Cow, 犬, 马, Pig, 兔 WB, IP, IHC, IF, IHC (p), ChIP, PLA 宿主: 兔 Polyclonal unconjugated
anti-PHD Finger Protein 8 (PHF8) (AA 195-351) antibodyPHF8 适用: 小鼠 WB, IP, ICC, IHC 宿主: 兔 Polyclonal unconjugated
anti-PHD Finger Protein 8 (PHF8) antibodyPHF8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- PHF8 (PHD Finger Protein 8 (PHF8))
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别名
- PHF8
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背景
- ZNF,Phf,KIAA,KIAA1111,ZNF422,PHF8,PHF8 is a histone lysine demethylase that functions as a transcriptional activator by specifically demethylating a number of repressive histone methylation marks: mono- and Dimethyl-histone H3 Lys9 (H3K9me1 and H3K9me2), Dimethyl-histone H3 Lys27 (H3K27me2) and Monomethyl-histone H4 Lys20 (H4K20me1). PHF8 contains an N-terminal zinc finger-like PHD domain that binds Trimethylated histone H3 Lys4 (H3K4Me3) and a C-terminal jumonji domain that is responsible for the demethylase activity. PHF8 is highly expressed in prostate cancer, laryngeal squamous cell carcinoma, and human non-small-cell lung cancer (NSCLC). Its expression is predictive of poor survival. Overexpression of PHF8 increases cell proliferation and cell motility, while silencing of PHF8 reduces cell proliferation, migration, and invasion. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 118 kDa
Observed MW: 140 kDa The actual band is not consistent with the expectation.
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UniProt
- Q9UPP1
抗原
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