Recombinant PEG10 抗体
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北京 101111
Quick Overview for Recombinant PEG10 抗体 (ABIN7828446)
抗原
See all PEG10 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant PEG10 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human PEG10 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- PEG10 (Paternally Expressed 10 (PEG10))
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别名
- PEG10
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背景
- PEG,RTL,Mart,RGAG,SIRH,KIAA,PEG10,EDR,HB-1,MEF3L,2-Mar,Mart2,RGAG3,RTL2,SIRH1,KIAA1051,MEF3L1,Paternally expressed gene 10(PEG10 ) is an imprinted gene which is derived from a Ty3/Gypsy long terminal repeat (LTR) retrotransposon family encoding Gag- and Pol-like domains. Deletion of PEG10 in mice leads to embryonic lethality due to defects in placental formation. PEG10 is aberrantly expressed in several cancer types, including hepatocellular carcinoma, and contributes to tumorigenesis by affecting cell proliferation, apoptosis, and metastasis. The PEG10 gene has two overlapping open reading frames that are regulated by the programmed process of -1 frameshifting. The first encoded protein ORF1 (or RF1) has a Gag domain with coiled-coil domain and zinc finger domains, while ORF1-2 (or RF1/RF2) is produced by -1 frameshifting and creates a fusion of the ORF1 Gag domain with a carboxyl-terminal Pol-like protease domain. PEG10 has retained the ability to form virus-like particles (VLPs) that are secreted as small extracellular vesicles delivered to distant sites. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 55/100 kDa
Observed MW: 55/100 kDa
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UniProt
- Q86TG7
抗原
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