Recombinant MYCN 抗体
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北京 101111
Quick Overview for Recombinant MYCN 抗体 (ABIN7828415)
抗原
See all MYCN 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant N-Myc Monoclonal Antibody
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纯化方法
- Protein A purified
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亚型
- IgG, kappa
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anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 401-464) antibody
MYCN 适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 168-267) antibodyMYCN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 337-464) antibodyMYCN 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2A4E9 unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 1-100) antibodyMYCN 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3H4 unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) antibodyMYCN 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (Internal Region) antibodyMYCN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) antibodyMYCN 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 1-464) antibodyMYCN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 1-100) antibodyMYCN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H4 unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (C-Term) antibodyMYCN 适用: 人 WB, ChIP-seq 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:50000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- MYCN (N-Myc Proto-Oncogene Protein (MYCN))
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别名
- N-Myc
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背景
- BHLHe,MODED,N-myc,NMYC,ODED,bHLHe37,MYCN,Class E basic helix-loop-helix protein 37,N myc,N myc proto oncogene protein,Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene,Neuroblastoma MYC oncogene,NMYC proto oncogene protein,N-myc proto-oncogene protein,Oncogene NMYC,pp65/67,V myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog,v myc avian myelocytomatosis viral related oncogene neuroblastoma derived,v myc myelocytomatosis viral related oncogene neuroblastoma derived,Members of the Myc/Max/Mad network function as transcriptional regulators with roles in various aspects of cell behavior, including proliferation, differentiation, and apoptosis. These proteins share a common basic-helix-loop-helix leucine zipper (bHLH-ZIP) motif required for dimerization and DNA-binding. Max was originally discovered based on its ability to associate with c-Myc and found to be required for the ability of Myc to bind DNA and activate transcription. Subsequently, Max has been viewed as a central component of the transcriptional network, forming homodimers as well as heterodimers with other members of the Myc and Mad families. The association between Max and either Myc or Mad can have opposing effects on transcriptional regulation and cell behavior. The Mad family consists of four related proteins, Mad1, Mad2 (Mxi1), Mad3, and Mad4, and the more distantly related members of the bHLH-ZIP family, Mnt and Mga. Like Myc, the Mad proteins are tightly regulated with short half-lives. In general, Mad family members interfere with Myc-mediated processes, such as proliferation, transformation, and prevention of apoptosis by inhibiting transcription.In humans the Myc family consists of 5 genes: c-Myc, N Myc, L-Myc, R-Myc, and B-Myc. While c-Myc is expressed in many proliferating cells, N-Myc expression is very restricted, with highest levels in during embryonic development and then in the adult during B-cell development. These expression patterns and results from targeted deletion of N-Myc suggest that N-Myc plays an important role in tissue development and differentiation. In addition, amplification or overexpression of N-Myc has been found in human neuroblastomas and is associated with rapid progression and poor prognosis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 50 kDa
Observed MW: 62 kDa The actual band is not consistent with the expectation.
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UniProt
- P04198
抗原
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