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Recombinant KARS 抗体

The 兔 单克隆 anti-KARS antibody is suitable to detect KARS in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, IF 和 IP.
产品编号 ABIN7828367
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant KARS 抗体 (ABIN7828367)

抗原

See all KARS 抗体
KARS (Lysyl-tRNA Synthetase (KARS))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This KARS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

A291
  • 原理

    Recombinant LysRS Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human LysRS fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50,IP 1:25-1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    KARS (Lysyl-tRNA Synthetase (KARS))

    别名

    LysRS

    背景

    DFNB,KIAA,KARS,CMTRIB,DFNB89,KARS1,KARS2,KRS,EC 6.1.1.6,KARS 1,KARS 2,Lysine tRNA ligase,Lysine--tRNA ligase,LysRS,Lysyl-tRNA synthetase,SYK,KIAA0070,Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA3(Lys), the primer for reverse transcription initiation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 75 kDa

    Observed MW: 75 kDa

    UniProt

    Q15046
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