Recombinant KARS 抗体
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北京 101111
Quick Overview for Recombinant KARS 抗体 (ABIN7828367)
抗原
See all KARS 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant LysRS Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human LysRS fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50,IP 1:25-1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- KARS (Lysyl-tRNA Synthetase (KARS))
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别名
- LysRS
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背景
- DFNB,KIAA,KARS,CMTRIB,DFNB89,KARS1,KARS2,KRS,EC 6.1.1.6,KARS 1,KARS 2,Lysine tRNA ligase,Lysine--tRNA ligase,LysRS,Lysyl-tRNA synthetase,SYK,KIAA0070,Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA3(Lys), the primer for reverse transcription initiation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 75 kDa
Observed MW: 75 kDa
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UniProt
- Q15046
抗原
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