Recombinant CDH6 抗体
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北京 101111
Quick Overview for Recombinant CDH6 抗体 (ABIN7828332)
抗原
See all CDH6 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Cadherin-6 Monoclonal Antibody
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纯化方法
- Protein A purified
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亚型
- IgG, kappa
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应用备注
- WB 1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- CDH6 (K-Cadherin (CDH6))
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别名
- Cadherin-6
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背景
- CAD,Cadherin 6 type,CADH,CAD6,CADH6,Cadherin 6,Cadherin 6 type 2,Cadherin 6 type 2 K cadherin (fetal kidney),Cadherin fetal kidney,Cadherin6,Cadherin-6,CDH 6,KCAD,K-Cadherin,Kidney Cadherin,CDH6,Cadherin-6, also known as kidney cadherin (K-Cadherin, CDH6) is a type II classical cadherin. While it was reported to have a tumor suppressor function in cholangiocarcinoma, cadherin-6 expression was shown to be a marker of epithelial mesenchymal transition, and positively correlated with stage and metastasis of papillary thyroid carcinoma. In related studies, cadherin-6 was shown to interact with GABARAP and related proteins to restrain autophagy, thereby promoting metastatic behavior. Cadherin-6 has since been proposed as an antibody-drug conjugate target for the treatment of ovarian and renal cancers. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 88 kDa
Observed MW: 130 kDa The actual band is not consistent with the expectation.
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UniProt
- P55285
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途径
- Cell-Cell Junction Organization
抗原
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